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Essays
Trust, Politics, and Meaning
Martin Gurri discusses trust and political polarization in the United States.
Issues
The Ethics of Human Challenge Trials: COVID-19 and Beyond
Could deliberately infecting consenting volunteers give us better vaccines and data about COVID-19? And should we do it?
Essays
The Case for Challenge Trials
Jessica Flanigan says that human challenge trials can solve many problems in fighting this and future pandemics.
Essays
Challenge Trials Are a Poor Substitute for an Effective Pandemic Response
Ben Bramble argues that challenge trials would be less of a help against COVID-19 than we may suspect.
Essays
SARS-CoV-2 Human Challenge Studies Should Not Be Permitted
Charles Weijer dissents sharply on the question of human challenge trials for COVID-19.
Essays
Reply to Bramble
Jessica Flanigan replies to Ben Bramble on the ethics of human challenge trials.